Premier League champions Manchester City are eyeing another deep run in the knockout stages of the UEFA Champions League in their quest to win it for the first time, but their Round of 16 opponent is an RB Leipzig team that has defeated the Citizens before.RB Leipzig have suffered only one lo s in their last 20 matches in all competitions and they downed Manchester City in the group stage of last season's tournament.Die Roten Bullen sit in fifth place in the Bundesliga, just four points behind leaders Bayern Munich, and they're a strong home side, scoring in all 16 of their home matches this season, including two or more goals in 13 of those contests.The absence of Manchester City playmaker Kevin De Bruyne could be a leveler in the first leg KeiVarae Russell Jersey of the aggregate-goal matchup in Germany. The decisive second leg is set for Tuesday, March 14 at the Etihad.MORE: This Champions League clash kicks off from Red Bull Arena in Leipzig Adam Trautman Jersey on Wednesday, February 22 at 9:00 p.m. local time.Here's how that time translates acro s some of the major territories:DateKickoff timeAustraliaThu, Feb. 2307:00 AEDTCanadaWed, Feb. 2215:00 ETHong KongThu, Feb. 2304:00 HKTIndiaThu, Feb. 2301:30 ISTMalaysiaThu, Feb. 2304:00 MYTNew ZealandThu, Feb. 2309:00 NZDTSingaporeThu, Feb. 2304:00 SGTUKWed, Feb. 2220:00 GMTUSAWed, Feb. 2215:00 ET Here's how to watch all of the action from this match in some of the major territories:TV channelStreamingAustraliaCanadaHong KongbeIN Sports 3beIN Sports ConnectIndiaSonyTEN 2Sony LIV, JioTVMalaysiabeIN Sports 3beIN Sports Connect, sookaNew ZealandSpark SportSingaporebeIN Sports 3beIN Sports Connect, StarHub TVUKBT Sport 1, BT Sport UltimateBT Sport app/siteUSACBS, UniMas, TUDN , Paramount+,ViX+Australia:Fans can watch every match of theUEFA Champions League with all the action .Canada:Every Champions League match in Canada can be .UK:The UEFA Champions League is carried by BT Sport's TV and streaming platforms.USA:Fans in the USA can watch the RB Leipzig vs. Man City match in English (CBS and Paramount+) and Spanish (UniMas, TUDN, and ViX+).When matches are televised on CBS or Univision TV outlets, those , which is available on a free trial for new users.MORE: RB Leipzig coach Marco Rose has star forwardChristopher Nkunku on the bench after the France international made his comeback against Wolfsburg at the weekend but then suffered a knock in training. Playmaker Dani Olmo is unavailable Erik Mccoy Jersey due to a thigh injury, and centre-back and PSG loaneeAbdou Diallo is out with a knee problem.RB Leipzig starting lineup (4-2-3-1): 21-Janis Blaswich (GK) 16-Lukas Klostermann, 4-Willi Orban, 32-Josko Gvardiol, 22-David Raum 27-Konrad Laimer, 24-Xaver Schlager 17-Dominik Szboboszlai, 10-Emil Forsberg, 11-Timo Werner 19-Andre SilvaRB Leipzig subs:13-Orjan Nyland (GK), 23-Marcel Halstenberg, 2-Mohamed Simakan, 25-Sanou sy Ba, 39-Benjamin Henrichs, 8-Amadou Haidara, 44-Kevin Kampl, 18-Christopher Nkunku, 9-Yu suf PoulsenPlaymaker Kevin De Bruyne and defender Aymeric Laporte both stayed back in Manchester due to illne s.John Stones is also out with a hamstring injury.Man City starting XI (4-3-3): 31-Ederson (GK) 2-Kyle Walker,25-Manuel Akanji, 3-Ruben Dias, 6-Nathan Ake 20-Bernardo Silva, 16-Rodri, 8-Ilkay Gundogan Marquez Callaway Jersey 26-Riyad Mahrez, 9-Erling Haaland, 10-Jack GrealishMan City subs: 18-Stefan Ortega (GK), 33- Scott Carson (GK) 82-Rico Lewis, 21-Sergio Gomez, 4-Kalvin Phillips, 32-Maximo Perrone, 62-Shea Charles, 93-Alex Robertson, 47-Phil Foden, 80-Cole Palmer, 19-Julian Alvarez The betting market pegs Manchester City as the heavy favorites to win this first Willie Roaf Jersey leg on the road, but bettors are on the fence as to whether we'll see a high-scoring match at Red Bull Arena or a defensive struggle in the first leg.Prediction: 1-1 drawUSA( )UK(SkyBet)Australia( )Canada()RB Leipzig win+33310/34.204.88Draw+25013/53.503.85Manchester City win-1204/51.851.66Over/Under2.5 goals-115/ -12010/11, 4/51.88/ 1.851.86/ 1.91Both teams to score Y/N-125/ -1154/6, 11/101.75/ 1.951.73 / 1.87